While Drogoz is flying, skirt his attacks with "Weightless". The "Aerobatics" legendary works well here. You can attack him back once he has landed, as he moves very slowly on foot.
Ruckus is a good champion to use "Reversal" on; it might even outright kill him when he's using his ultimate.
Try to get in front of him quickly when he's already firing on your teammates, but be sure to have an equally fast escape!